Part 1, From Cells to Society: Research in the time of COVID-19

The schedule of themed issues for the Delaware Journal of Public Health is set to close up to a year in advance of the publication date. Like many others, the Journal was impacted by COVID-19, and we utilized the opportunity to publish this two part issue on “Current Research,” with a focus on the groundbreaking research in our community.”

Soon after the COVID-19 pandemic started, we convened with this issue’s Guest Co-Editors Mia Papas, Ph.D. and Steven Stanhope, Ph.D. to focus on research- of all sorts- specific to the novel coronavirus. They did a masterful and comprehensive review of Delaware research that covers the depth and breadth of public health, population health, clinical research, and interventions – and we thank them for their effort. The final title of this two part issue dynamically captures what it is all about:

“FROM CELLS TO SOCIETY: RESEARCH IN THE TIME OF COVID-19”

We still included other research articles submitted to us – a validation that while COVID-19 is the big news, other work continues. You’ll read about that work in part 2 of this issue.

Article 1. In this Issue
Omar A. Khan, M.D. MHS and Timothy E. Gibbs, MPH

Article 2. Guest Editors: From Cells to Communities: Addressing COVID-19 in Delaware Through Scientific Research
Mia Papas, Ph.D. and Steven Stanhope, Ph.D.

Article 3. Coronavirus through Delaware’s Computational Microscope
Carolina Pérez Segura, Nidhi Katyal, Ph.D., Fabio González-Arias, Alexander J. Bryer, Juan R. Perilla, Ph.D.,  and Jodi A. Hadden-Perilla, Ph.D.

Article 4. Rapid Development and Validation of a Novel Laboratory-derived Test for the Detection of SARS-CoV-2
James Saylor, Jennifer Mantle, Leila H. Choe, Alana Szkodny, Vipsa Mehta, Alaina Meadows, Cynthia Flynn, Leslie Taylor, Abraham Joseph, Brewster Kingham, and Kelvin H. Lee

Article 5. Validation and Use of Point-of-Care Lateral Flow Chromatographic Immunoassays for Early Diagnostic Support During the COVID-19 Pandemic
Richard M. Pescatore, D.O., Lisa M.G. Henry, M.H.S.A., Rebecca D. Walker, Ph.D., J.D., M.S.N., William Chasanov, D.O., M.B.A., Christopher M. Gaeta, Crystal Mintzer Webb, M.P.A., Camille Moreno-Gorrin, M.S., Paula Eggers, Frederick P. Franze, M.T. (A.S.C.P.), Sergio Huerta, M.D., Christina Pleasanton, M.S. Molly Magarik, Karyl T. Rattay, M.D., M.S., Kara Odom Walker, M.D., M.P.H., M.S.H.S., and Rick Hong, M.D.

Article 6. The Importance of Research in Addressing the COVID-19 Pandemic: Focus on the Use of Serology Testing
Vicky L. Funanage, Ph.D.

Article 7. Perspectives on Molecular Diagnostic Testing for the COVID-19 Pandemic in Delaware
Erin L. Crowgey, Mary M. Lee, Brett Sansbury, and Eric B. Kmiec

Article 8. Rapid COVID-19 Prognostic Blood Test for Disease Severity Using Epigenetic Immune System Biomarkers
Adam G. Marsh, G. Mark Anderson, and Erich J. Izdepski

Article 9.  Engineering Preclinical Tools and Therapeutics to Understand and Treat COVID-19
Catherine A. Fromen, and Jason P. Gleghorn

Article 10. Multisystem Inflammatory Syndrome in Children (MIS-C): an emerging immune mediated syndrome in children associated with COVID-19
Deepika Thacker, M.D.

Article 11. Assessing the Impact of COVID-19 on Children and Youth
Lee M. Pachter, D.O., Cynthia Garcia Coll, Ph.D., Norma J. Perez-Brena, Ph.D., Lisa M. Lopez, Ph.D., Linda C. Halgunseth, Ph.D., Rashmita S. Mistry, Ph.D., Gabriela Livas Stein, Ph.D., and Gustavo Carlo, Ph.D.

Article 12. Epidemic Meets Pandemic: Treating Opioid Use Disorder in the Age of COVID-19
Kimberly D. Williams, M.P.H., Lee M. Pachter, D.O., and Scott D. Siegel, Ph.D., M.H.C..D.S.

Article 13. Mental Health Crisis: Depression, Anxiety, and COVID-19
Bernard Shalit, and Marina Gettas, Dr.P.H., M.P.H.

Article 14. Courage, Cancer and COVID
Carol Kerrigan Moore, MS

Article 15. Design of Clinical Trials Evaluating Ruxolitinib, a JAK1/ JAK2 Inhibitor, for Treatment of COVID-19–Associated Cytokine Storm
Peter Langmuir, M.D., Swamy Yeleswaram, Ph.D., Paul Smith, Ph.D., Barbara Knorr, M.D., and Peg Squier, M.D., Ph.D.

Article 16. The Power of Public Health Surveillance
Rick Hong, M.D., Rebecca Walker, Ph.D., J.D., M.S.N., Gregory Hovan, Lisa Henry, M.H.S.A., and Rick Pescatore, D.O.

Article 17. A Need for Contact Tracing Research
Stephanie Shell, M.S.S.

Article 18. Mapping the ChristianaCare response to COVID-19: Clinical insights from the Value Institute’s Geospatial Analytics Core
Madeline Brooks, M.P.H., Chenesia Brown, M.A., Ph.D.(c), Wei Liu, Ph.D., and Scott D. Siegel, Ph.D., M.H.C.D.S.

Article 19. Social Determinants of Health, From Assessment to Action: A Review of 3 Studies from the Value Institute at ChristianaCare
Cecelia Harrison, M.P.H., Madeline Brooks, M.P.H., and Jennifer N. Goldstein, M.D., M.Sc.

Article 20. Race as a Social Determinant of Health: Lessons from the Coronavirus Pandemic in Delaware
Daniel G. Atkins, J.D., David P. Donohue, M.D., F.A.C.P., Robert L. Hayman, Jr., Leland Ware, J.D., and Maija Woodruff

Article 21. Addressing COVID-19 Health Disparities Through Community Engagement
Marshala Lee, M.D., M.P.H., Jacqueline Ortiz, M.Phil., and Jacqueline Washington, Ed.D.

Article 22. Engaging Community Health Workers and Social Care Staff as Social First Responders during the COVID-19 Crisis
Alicia L. Salvatore, Dr.P.H., M.P.H., Jacqueline Ortiz, M.Phil., Erin Booker, L.P.C., Nora Katurakes, M.S.N., R.N., O.C.N., Christopher C. Moore, Carla P. Aponte Johnson, M.S., Alexandra M. Mapp, M.P.H., Alex Waad, M.A., and Michelle L. Axe, M.S., C.H.E.S.

Article 23. Delaware COVID-19 Homeless Community Outreach Partnership 2020
Rita Landgraf, Susan Holloway, Renee Beaman, and Ray Fitzgerald